The Great Plains Laboratory is pleased to announce the availability
of a critical new test:DPP IV-Dipeptidyl
Peptidase IV-Master regulatory enzyme.
Clinical abnormalities documented in:
Depression · Rheumatoid disorders
Alcoholism · HIV infection
Eating disorders · Anxiety
Schizophrenia · Celiac disease
Cholestasis
Probable useful applications:
Candida related disorders
Juvenile diabetes
Wheat and milk sensitivity
Sample requirement: 1 ml serum
Prices:
Insurance price-$100
Cash price-$75
References:
Maes M, Lin A, Bonaccorso S, Vandoolaeghe E, Song C, Goossens F, De
Meester I, Degroote J, Neels H, Scharpe S, Janca A. Lower activity of
serum peptidases in abstinent alcohol-dependent patients. Alcohol 1999
Jan; 17(1):1-6
Smith MW, Phillips AD. Abnormal expression of dipeptidylpeptidase
IV activity in enterocyte brush-border membranes of children suffering
from coeliac disease. Exp Physiol 1990 Jul;75(4):613-6
Tiruppathi C, Miyamoto Y, Ganapathy V, Leibach FH.Genetic evidence
for role of DPP IV in intestinal hydrolysis and assimilation of prolyl
peptides. Am J Physiol 1993 Jul;265(1 Pt 1):G81-9
Hildebrandt M, Rose M, Mayr C, Schuler C, Reutter W, Salama A, Klapp
BF
Alterations in expression and in serum activity of dipeptidyl peptidase
IV (DPP IV, CD26) in patients with hyporectic eating disorders. Scand
J Immunol 1999 Nov;50(5):536-41
Mentlein R Dipeptidyl-peptidase IV (CD26)--role in the inactivation
of regulatory peptides. Regul Pept 1999 Nov 30;85(1):9-24
Morimoto C, Schlossman SF.The structure and function of CD26 in the
T-cell immune response. Immunol Rev 1998 Feb;161:55-70
Elgun S, Keskinege A, Kumbasar H. Dipeptidyl peptidase IV and adenosine
deaminase activity. Decrease in depression. Psychoneuroendocrinology
1999 Nov;24(8):823-32
Stefanovic V, Vlahovic P, Savic V, Ilic S, Mitic-Zlatkovic M Kidney
ectopeptidases in gentamicin and mercuric chloride-induced acute renal
failure. Cell Physiol Biochem 1998;8(5):278-84
Perner F, Gyuris T, Rakoczy G, Sarvary E, Gorog D, Szalay F, Kunos
I, Szonyi L,
Peterfy M, Takacs L Dipeptidyl peptidase activity of CD26 in serum and
urine as a marker of
cholestasis: experimental and clinical evidence. J Lab Clin Med 1999
Jul;134(1):56-67
Kozakova H, Stepankova R, Kolinska J, Farre MA, Funda DP, Tuckova
L,
Tlaskalova-Hogenova H Brush border enzyme activities in the small intestine
after long-term gliadin feeding in animal models of human coeliac disease.
Folia Microbiol (Praha) 98;43(5):497-500
Hosono O, Homma T, Kobayashi H, Munakata Y, Nojima Y, Iwamoto A, Morimoto
C Decreased dipeptidyl peptidase IV enzyme activity of plasma soluble
CD26 and its inverse correlation with HIV-1 RNA in HIV-1 infected individuals.
Clin Immunol 1999 Jun; 91(3):283-95
Kullertz G, Kallenbach W, Kullertz G, Fischer G Post-proline hydrolysis
activities in cerebrospinal fluid. Z Med Lab Diagn 1989;30(5):273-80
Suzuki Y, Erickson RH, Sedlmayer A, Chang SK, Ikehara Y, Kim YS Dietary
regulation of rat intestinal angiotensin-converting enzyme and dipeptidyl
peptidase IV. Am J Physiol 1993 Jun; 264(6 Pt 1):G1153-9
Maes M, Goossens F, Lin A, De Meester I, Van Gastel A, Scharpe S
Effects of psychological stress on serum prolyl endopeptidase and dipeptidyl
peptidase IV activity in humans: higher serum prolyl endopeptidase activity
is related to stress-induced anxiety. Psychoneuroendocrinology 1998
Jul;23(5):485-95
Perner F, Gyuris T, Rakoczy G, Sarvary E, Gorog D, Szalay F, Kunos
I, Szonyi L, Peterfy M, Takacs L Dipeptidyl peptidase (DPP) activity
is elevated in the urine and serum of patients with biliary atresia
(BA). J Lab Clin Med 1999 Jul;134(1):56-67
Hildebrandt M, Rose M, Mayr C, Schuler C, Reutter W, Salama A, Klapp
BF
Alterations in expression and in serum activity of dipeptidyl peptidase
IV (DPP IV, CD26) in patients with hyporectic eating disorders. Scand
J Immunol 1999 Nov;50(5):536-41
