multiple sclerosis

UNDERSTANDING MULTIPLE SCLEROSIS

Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system and is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells. This nerve damage is caused by inflammation, most likely due to a virus, gene defect, environmental factors, or a combination of these issues. You are more likely to have MS if you have a family history of it or live in a part of the world where it is more common. The disease affects women more than men.  Symptoms vary but can include problems using arms or legs, balance and coordination issues, constipation and stool leakage, uncontrollable rapid eye movements, decreased attention span, memory loss, depression, speech difficulty, fatigue and many more. Episodes can last for days, weeks or months. Some people with MS experience a time when symptoms go into remission, and many relapse.

Clinical studies have shown that the physical conditions associated with MS are also associated with oxidative stress, mineral deficiency, and microbial imbalance. Often, these abnormalities are not identified through routine lab work and are dismissed as insignificant when they are discovered. The reality is that the specific concentration of the mineral balance in the body has a profound effect on the response of the immune and nervous systems. Furthermore, individuals prone to inflammation and oxidative stress are more susceptible to opportunistic pathogens. These pathogens can hinder (either directly or indirectly) proper digestion/absorption and create further oxidative stress and mineral deficiency in the body. Unless properly addressed, this vicious cycle will continue to inhibit the various chemical pathways necessary for proper neurological and immune function. The resulting complications will contribute to, and may even cause, the symptoms of MS.



CLINICAL SIGNIFICANCE

ORGANIC ACIDS TEST

Reducing or eliminating yeast overgrowth can be an effective method of reducing autistic symptoms. Microbial overgrowth can be measured by urine organic acid analyses of yeast and bacterial metabolites. The Organic Acids Test quantifies other useful markers of energy cycle and neurological function, as well as nutritional adequacy. The test is also designed to identify some rare genetic diseases and indirect indicators of methylation problems. When Candida grows out of balance, it can disrupt areas of the intestinal wall, producing toxins and leading to leaky gut syndrome. Candida toxins can depress the immune system. An inflammatory immune response and multiple food sensitivities can result from the leaky gut. Many children on the autism spectrum have an overgrowth of certain Clostridia species, which produces a compound called HPHPA (3-(3-hydroxyphenyl)- 3-hydroxypropionic acid).[2] HPHPA may disrupt dopamine metabolism by interfering with the enzyme dopamine beta-hydroxylase. HPHPA is a potent toxin with profound neurological effects in autism, and can lead to moodiness, tantrums, extreme anxiety, aggression, and /or selfinjurious behavior.[3]

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METALS HAIR TEST

Symptoms of autism are consistent with those of a mercury toxicity.[4] Metal toxicity impacts cognition, language, immunity, and behavior. Identifying and eliminating metals such as lead, arsenic, aluminum, and mercury is an important step toward recovery. Evidence shows that children with autism tend to have low levels of glutathione and cysteine, which are critical to the removal of toxic metals like mercury. Children with autism are also frequently treated excessively with oral antibiotics, which greatly inhibits excretion of mercury.

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IGG FOOD ALLERGY + CANDIDA

Most of the time, food reactions are IgG-mediated. These sensitivities tend to create problems because they stress the child's immune system, compromising digestion and resulting in inflammation and increased behavioral issues.[3] IgG food allergy testing can identify the specific antibody reactions not commonly tested by allergists. Eliminating offending foods strengthens the immune system and may help significantly reduce autistic symptoms and GI problems. The use of probiotics may also be beneficial in alleviating GI dysfunction, inflammation, and potential behavioral symptoms shown by some children on the autism spectrum.[5]

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GLUTEN / CASEIN PEPTIDES

About 60% of children with autism have shown adverse reactions to proteins found in wheat (gluten) and dairy (casein) products.[6] The Peptides Test measures small protein fragments called neuro-peptides that bind to opiate receptors in the brain. These opiate peptides are partially digested proteins that have the potential to interfere with neurotransmission, resulting in cognitive difficulty and speech impairment. Worsening neurological symptoms have been reported in autistic patients after consumption of milk and wheat. In one study, the behavioral symptoms of most patients greatly improved after a period of 8 weeks on an elimination diet.[7]

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ADVANCED CHOLESTEROL PROFILE

Cholesterol is essential to brain development, and is one of the healthy fats required for myelination of the brain and for the health and repair of cell membranes. Cholesterol supports adrenal pathways and sex hormone production, and is also critically important in improving the efficiency of oxytocin receptors in the brain. The majority of kids on the spectrum have a problem with oxytocin function, which can result in problems with socialization and cause symptoms of anxiety.[3] Identifying and treating low cholesterol levels with cholesterol supplementation can significantly improve the symptoms of autism.

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COMPREHENSIVE STOOL ANALYSIS

Comprehensive stool analysis detects the presence of pathogenic yeast, parasites, and bacteria that could be contributing to chronic illness and neurological dysfunction. The test evaluates overall intestinal function and beneficial bacterial levels, and indicates which agents will be most effective in killing harmful bacteria and yeast.

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