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I nostri esami Scegliere analisi L'analisi degli acidi organici Acidi organici, versione corta Cultura di lieviti con sensibilità COMBO di AAO+Cultura COMBO di AAOcorta +Cultura Peptidi di glutine/caseina Aminoacidi Acidi grassi essenciali Allergie alimentari, completa Allergie respiratorie, corta Allergie respiratorie, completa Deficienza immune Zinco Metalli nel sangue Metalli nei capelli Metalli nell'urina Livelli di vitamine(12) Livelli di vitamine (20) Anticorpi di trans-gutaminase Analisi completa di feci Acido urico DPP IV-Dipeptidil Peptidasa Analisi degli Anticorpi allo Streptococco

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Ordinare recipienti di prelievi Comprare integratori nutritivi Libreria di GPL (Inglese e Spagnolo) Comprare Libri

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Informazione sulle condizioni mediche

Autismo/PDD DDA/DDAH Disturbi intestinali Candida Malattia Celiaca Fatica cronica Sindrome di Down Dysbiosis Infezioni d'orecchie Fibromialgia Allergie alimentari Glutine/Caseina Sistema immune Metalli tossici Schizofrenia Proliferazione di lieviti

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Great Plains Laboratory, Inc.
© 1996-2002 All Rights Reserved

Domande Frequenti

Ci vuole avere l'approvazione di un dottore per fare analisi al Laboratorio Great Plains?

No. Benché sia raccomandabile non c'è bisogno di avere un dottore che firmi il modulo di richiesta per realizzare le nostre analisi. L'unica eccezione sono i pazienti che abitano negli Stati Uniti, in cui caso ammettiamo approvazioni di medici (M.D.), osteologhi (D.O.), infirmiere (nurse practitioner), chiroterapeuti (D.C.) e naturopati (N.D.).

Sono interessato a fare le analisi. Cosa devo fare adesso?

Per cominciare è necessario avere i nostri kit per fare il prelievo e per inviare i campioni agli Stati Uniti, perciò ci voule ordinare i nostri kit.
Questo può essere fatto nella pagina di inizio del nostro sito web sotto il titolo ORDINARE RECIPIENTI DI PRELIEVI oppure può inviare la seguente informazione all'indirizzo e-mail wcastillo@gpl4u.com:

- Nome e cognome del paziente.
- Data di nascita del paziente.
- Indirizzo per consegnare i kits.
- Numero di telefono.
- Numero di carta di credito e data di scadenza per pagare le despese della spedizione dei kits fra gli Stati Uniti e la Sua nazione.
- Analisi che realizzerà.
- Suo nome e cognome.

I kits sono inviati tramite la FedEx e arriveranno da Voi fra 5 e 10 dopo fare l'ordine dei kits.

Come faccio il prelievo? Come posso avere più informazioni in caso di dubbi?

Nei kits vengono, insieme ai recipienti, tutte le istruzioni dettagliate in italiano. Nel caso di campioni di urina, feci e capelli potete fare il prelievo a casa, nel caso di prelievi di sangue è importante di andare a un laboratorio specializzato nel prelievo di sangue da bambini.
In caso di avere qualsiasi domanda potete scrivere in italiano all'indirizzo wcastillo@gpl4u.com.

Come faccio il pagamento delle analisi?

Come si fa la spedizione dei kit?

Quando riceverò i risultati? Come li riceverò?

Riceverò tutti i risultati delle analisi in italiano?

Cosa succede nel caso che i campioni avranno problemi oppure se l'addebito dalla mia carta di credito non può essere fatto?

Il Great Plains può aiutarmi con l'interpretazione dei risultati?

Il mio dottore stabilisce che tutte le persone hanno lieviti nel loro intestino. Perchè non tutti sono malati?

The most important question is not whether yeast are present or not. The critical factors are the quantity of yeast and the kinds and amounts of toxic products they produce. Everyone in this society has carbon monoxide in his or her blood from auto exhaust and secondhand cigarette smoke and can tolerate a low value. When the amount of carbon monoxide increases, some individuals feel depressed, some have headaches, some develop muscle weakness, some feel tightness in the chest or angina, some experience nausea and vomiting, some become dizzy, some develop dimming of vision. As values further increase, symptoms may include convulsions, coma, respiratory failure, and death. Some individuals who recover from severe carbon monoxide poisoning may suffer residual neurological damage. Different people will respond with different symptoms to the same concentration of carbon monoxide.

Perchè è sorprendente che l'esposizione a una grande varietà di prodotti di lieviti tossici in tempi differenti e ad età differenti produce sintomi differenti?

If I suggested that there were a carbon monoxide connection with all of the diverse symptoms associated with carbon monoxide exposure, no one would challenge me. The reason that the carbon monoxide connection is accepted is because carbon monoxide can be easily measured in blood. The toxic yeast byproducts were only recently discovered. As knowledge of them increases, acceptance of the yeast-related illnesses will increase.

Mio bambino sta in un trattamento con antibiotici. Devo aspettare fino al termine del trattamento per fargli fare l'analisi?

An assumption is frequently made that if the child has a significant yeast overgrowth of the intestine while on antibiotics that the yeast overgrowth will disappear when the antibiotics are stopped. However, this is not necessarily the case and the yeast overgrowth may even become worse especially if the person is on a high sugar, high carbohydrate diet. There is no evidence that the yeast overgrowth will spontaneously disappear on its own. Furthermore, the yeast overgrowth may be suppressing the immune system, preventing your child from recovering from the infection. The sooner the yeast problem is controlled, the sooner the vicious cycle of antibiotics and frequent infections may be broken.

Perchè devo fare l'Analisi di Acidi Organici? Perchè non comincio direttamente con Nistatina?

Some children with autism don't have the yeast problem but may have an overgrowth of the Clostridia bacteria. Treating these children with an antifungal could make the bacteria problem even worse. Also, if your child has the yeast problem, he will likely require major changes in his diet (and that of your family) and drug therapy for six months or longer. I think that it will be very difficult to make a commitment to the diet and drug therapy if you are nor even sure if your child has the yeast problem. Your child could have a yeast overgrowth with drug-resistant yeast and if you don't do the testing beforehand, it would be difficult to know what is happening. Also, if the problem is severe, the yeast die-off reaction may be more severe and you may want to take additional steps to control the yeast before using antifungals. And it may be very difficult to get your doctor's cooperation for the prescriptions and insurance reimbursement if there is no evidence that the yeast problem even exists.

Mi ho fatto fare l'Analisi di Acidi Organici prima in un altro laboratorio. Perchè non posso ottenere la stessa informazione dell'altra analisi?

No. No other laboratory routinely analyzes the same compounds as this laboratory. Most test for the inborn errors of metabolism and that's all.

I have an HMO and they have to send the test to a certain lab. Is that OK?

No. No other laboratory routinely analyzes the same compounds as this laboratory including Labcorp, SmithKline, or Mayo Medical laboratories. If you do not specify our laboratory, your child's urine will be sent to one of the large reference labs, which cannot accurately evaluate your child's condition. Most test for some of the inborn errors of metabolism and that's all.

Do most insurance companies reimburse for your test?

Yes, but we cannot guarantee how much (if any) reimbursement will be given. Most HMO's will pay but you may need some additional documentation to get payment. Use the information in this book to indicate to your HMO why no other labs are acceptable.

What about reimbursement for Medicaid and Medicare?

The Great Plains Laboratory is now set up for Medicare but does not yet have Medicaid authorization. Medicaid reimbursement has different regulations in each state, which makes the paperwork to get established very difficult and time-consuming.

Posso fargli fare mio figlio l'analisi? Egli ha avuto infezioni alle orecchi con frequenzaCan I test my infant who is having frequent ear infections or other frequent infections and who now seems "spacey" to see if they are developing the abnormal yeast byproducts?

Yes. The Great Plains Laboratory provides tape-on bags to collect the urine from infants or children who are not potty trained.

Mio figlio ha molte allergie alimentari. Ciò può essere collegato al problema dei lieviti? A quale punto devo fargli fare l'analisi di allergie alimentari?

Yeast can exist in two forms: a floating single cell form or a colony form. When yeast form colonies, they secrete enzymes such as phospholipase and proteases that break down the lining of the intestinal tract in order to attach the yeast colony to the intestinal wall. The holes made by the yeast produce a condition called leaky gut syndrome in which large undigested food molecules are absorbed into the bloodstream and elicit food allergies. Once the underlying yeast problem is controlled, the holes in the intestine will heal. Then less undigested food gets into the blood and the number of food allergies will decrease.

Le analisi di allergie alimentari del Great Plains Laboratory valutano la sensibilità del frumento e dei latticini?

Yes, both the basic and comprehensive food allergy tests check for wheat and dairy sensitivity. We have found that children with autism have increased amounts of IgG antibodies to both wheat and dairy.

Dovrei fare entrambi l'analisi di allergie alimentari in sangue e l'analisi di peptidi in urine?

Most children with autism have both elevated IgG antibodies to gluten and casein as well as elevated peptides in the urine. If the allergy test is positive, it is not essential to do the peptide test also. However, if the allergy tests for wheat and dairy are negative, it would be a good idea to do the peptide test.

Come sono collegate la sensitività al gluten e alla caseina che sono comune nell'autismo e in altre malattie al problema dei lieviti? Oppure sono due cose diverse?

There does appear to be some relationship between the two medical problems. Gluten and casein are proteins. Gluten is one of the major proteins in wheat. Casein is the major protein in milk and cheese but is an additive in a wide variety of other foods such as soup and TV dinners. If these proteins are absorbed before being completely digested, the undigested pieces of protein enter the brain and attach to opiate receptors in the areas of the brain controlling language and other areas of the brain and impair the brain function. These pieces of protein called peptides are eventually eliminated in the urine where they are measured.

The test is called the urinary peptide test. I suspect there would be less of a problem with these molecules if the yeast is controlled and am working to obtain a grant to test this hypothesis. In the meanwhile, I advise you to do the gluten/casein urinary peptide test or IgG food allergy tests for wheat and dairy products as soon as possible. The elimination of these foods is a difficult process and I would advise doing the urinary peptide test before implementing the diet. I think that you will be more highly motivated to implement the diet if you know there is a definite problem that cannot be controlled by other means.

Dove posso acquistare SuperNuthera (una combinazione di vitamina B-6, magnesio e altre vitamine)?

This product is available from Kirkman Sales Co, PO Box 1009, Wilsonville, OR 97070. The phone no is 888-KIRKMAN or 503 694-1600. E-mail is kirkman@portweb.com. The company provides a sheet indicating the recommended dosage and ways to give it in the food.

Questi medicamenti o alcuni dei integratori nutrizionali interferire con l'Analisi di Acidi Organici?

No, there is no interference from any known drug or supplement since the technology of mass spectrometry is the most accurate technology available. If your child takes vitamin supplements like vitamin C, then high concentrations of vitamin C will be detected in the urine. However, if antifungal supplements or drugs are taken before the test, you will probably get a lower value for the yeast byproducts. I advise you to get the test first so that you will know what the starting point is.

L'uso di Nistatina interattuarà adversativamente con altri medicamenti che il paziente sta Will the use of nystatin interact adversely with other medications the patient is taking?

Nystatin is not absorbed from the intestinal tract in any appreciable quantity unless extremely large doses are used. Therefore, there are no adverse reactions with drugs such as antiseizure medications, antidepressants such as Prozac or Elavil, or any other medications. If you use antifungals that are absorbed from the intestinal tract such as Lamisil, Sporanox, Diflucan, and Nizoral, then drug interactions must always be considered. Other drugs used simultaneously may be more potent or make the antifungal more potent when these latter drugs are used.

What about starting all of these therapies at the same time?

I recommend that the antifungal therapy precede the allergy and gluten/casein testing since the yeast may be making the situation worse. As far as the supplements such as SuperNuthera and DMG, I recommend that they be tried out before or after the antifungal therapy so that you can know which therapies have been most beneficial to your child. If you do everything simultaneously, you won't be able to say which therapy is most beneficial.

Could there be adverse reactions to the food colors and flavors in the nystatin?

Yes, that is a possibility. If that is the case, then you may have to use the pure nystatin powder and disguise it in food. One way to disguise it might be to combine it with fructo-oligosaccharides (FOS), an unusual sugar that cannot be utilized by the yeast, or with the herbal sweetener Stevia. FOS and Stevia are available in most large health food stores.

My child has a yeast infection in the genital or anal area. Does this indicate a yeast overgrowth of the intestinal tract?

Yes, but it is impossible to know for sure without testing to confirm it.

If my child has no external signs of yeast such as thrush, or anal or genital rashes, could he still have the yeast problem?

Yes, in many cases the behavioral abnormality is the only clue to the underlying yeast overgrowth of the intestinal tract.

My child has a white coating of the mouth. Could this be a yeast problem?

Yes. One of the most common yeasts in the intestine is Candida albicans. Albicans is a Latin word for white and a white coating of the tongue may very well be Candida.

Could intermittent low-grade fever be a symptom of yeast infection?

Fever often accompanies yeast infection of the blood stream, which is termed systemic yeast infection. To test for yeast in the blood, you need to have a yeast culture and/or yeast antibody tests on blood. Remember that these tests may give a high percentage of false negative results. Your child may also have an intestinal yeast overgrowth as well.

My insurance company won't reimburse for any lab test dealing with autism. What can I do?

Many different diagnoses that accurately describe the medical condition of your child can be used for insurance reimbursement and many times reimbursement can be obtained when an appropriate diagnosis is used.

I don't have insurance and can't afford the price. Can you help me?

We would be happy to work out an installment plan for you.

What foods have Lactobacillus acidophilus in them?

Yogurt is high in Lactobacillus acidophilus. The unflavored kind or plain is more highly recommended than the flavored because yeast may grow in the kind with fruit on the bottom. Some milk now also has acidophilus added. Just read the labels. However, most children with autism are sensitive to casein so the use of these sources may not be wise.

What kind of changes might I expect with the antifungal drug therapy?

Results are highly variable but the most usual improvement noted is increased focus and concentration. Other improvements may include increased and clearer vocalization, less stimming, decrease in aggressive or self-abusive behavior like head-banging, better sleep pattern, increased socialization, and more eye contact. Antifungal therapy may help individuals with normal or marginally elevated yeast metabolites but the percentage of those benefiting is lower than in individuals with high concentrations of these metabolites. Antifungal therapy is not usually a cure for autism by itself but may significantly improve the life of the child and his family. Antifungal therapy combined with other measures such as gluten and casein restriction, elimination of food allergies, and behavioral therapies have been successful in reversing autism in two cases in which these therapies were started at a very young age. Their accounts are included later in this book. Both of these successful families adopted very similar therapies completely independently of one another and started treatment about two years of age. Only large long-term studies will determine if these successes can be translated into successful therapies for the majority of children with autism.

How can the intestinal Clostridia overgrowth be controlled?

A number of children with autism with elevated Clostridia metabolites have responded favorably to treatment with Flagyl or vancomycin. However, in most cases Flagyl or vancomycin therapy is not needed in most cases. Just a supplement with 10-20 billion cells per day of Lactobacillus acidophilus GG may control this abnormality even in extreme cases. Lactobacillus acidophilus GG is available from both VRP (775 884-1300) and Klaire Laboratories (800 533-7255).

My child only eats bread, dairy products, cereal or pasta. How can I change his diet without starving my child?

Parents have reported to me that their children may refuse the altered diet for three or four days and then give in and eat the new foods. I think that it would be wise to consult your physician and/or a dietitian before starting the diet. I do not think a short time without eating is harmful to most children but might be significant if your child has special medical problems like diabetes. Some children have not adjusted well to the gluten/casein free diet and may have to go back to gluten or casein containing foods because of substantial weight loss on the restricted diets. Calcium supplementation is critical to children on a restricted diet.

How long will my child need to be on the antifungal therapy?

This is a difficult question that will only be answered by future research. I have personal knowledge that many children helped by antifungal therapy regress following the discontinuation of therapy even after six months to two years of antifungal treatment. This regression is virtually always accompanied by an increase in abnormal yeast metabolites. Discovering a way to overcome this resistance should be a national priority for future research. Call and write your congressmen in the House and Senate to inform them about this problem.

How often should I get my child re-tested?

As a general rule, every three months may be satisfactory. However, I recommend retesting be done sooner if there is the child does not respond favorably by the end of one month of antifungal therapy since the yeast or bacteria might be resistant to the drugs used for treatment.

Can I collect one urine sample and perform all the urine tests that you offer?

You can perform 3 of the 4 urine tests with one urine sample. If you have the urine kit for organic acids, peptide, and amino acids then you can do all of these tests as long as you collect at least 15 mls of urine (5 mls for each test). You will need a special collection kit to perform the urine metals test. The metals test requires at least 40 mls of urine.

When should I expect results from the tests?

All of the tests have different turn around times. Most of the tests are ready within 2 weeks. You will receive the results through the mail. The physician you indicated on the test request form will also receive the results. Once you do receive results, please call to set up a phone consultation to discuss them.

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