Celiac Disease Test
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General Description
This test recognizes an auto-immune antibody called the Transglutaminase Antibody (TGAB) that causes the immune system to attack proteins that belong to the individuals own body. The TGAB is a definitive test for Celiac Disease, a medical disorder characterized by a reduced ability to digest wheat. The disease causes a toxic effect from the protein gluten, found in wheat. Eating wheat causes destruction of the lining of the intestine for these individuals. Symptoms may include diarrhea, short stature, discolored dental enamel, depression, premature degeneration of the nervous system, seizures, arthritis, nutritional deficiencies due to malabsorption, and abdominal distension.
Click here to view the Recommendations By Disorder Chart (PDF)
Benefits of the Celiac Disease Test
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The test is considered the most specific test for celiac disease with near perfect specificities and sensitivities for celiac disease. |
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Knowledge to facilitate appropriate treatment |
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Consultation about results is included with each test at The Great Plains Laboratory. |
Recommendations
If the transglutaminase screening is positive and possible celiac disease is indicated, here are some recommendations:
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Restriction of gluten from the diet |
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Eating additional portions of meat, vegetables, and fruits |
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Diet supplementation, primarily with enzymes that aid in digestion of these foods |
Analyte List
Transglutaminase Antibody ─ definitive test for Celiac Disease
Specimen Requirements
2 mL of serum in a gold-topped SST or royal blue-topped no additive tube.
CPT Code
82492
Kit Instructions
For blood instructions please click here.
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