Celiac Disease Test

	General Description
	Analyte List
	Turn Around Time
	Specimen Requirements
	CPT Code
	Kit Instructions
	Sample Report
	Order Test

General Description

This test recognizes an auto-immune antibody called the Transglutaminase Antibody (TGAB) which causes the immune system to attack proteins that belong to the individuals own body. The TGAB is a definitive test for Celiac Disease, a medical disorder characterized by a reduced ability to digest wheat. The disease causes a toxic effect from the protein gluten, found in wheat. Eating wheat causes destruction of the lining of the intestine for these individuals. Symptoms may include diarrhea, failure to thrive, short stature, discolored dental enamel, depression, premature degeneration of the nervous system, seizures, arthritis, nutritional deficiencies due to malabsorption, and abdominal distension.

Click here to view the Recommendations By Disorder Chart (PDF)

Benefits of the Celiac Disease Test

	The test is considered the most specific test for celiac disease with near perfect specificities and sensitivities for celiac disease
	Knowledge to facilitate appropriate treatment
	Consultation about results is included with each test at The Great Plains Laboratory, Inc.

Recommendations

If the transglutaminase screening is positive and possible celiac disease is indicated, here are some recommendations:

	Restriction of gluten from the diet
	Eating additional portions of meat, vegetables, and fruits
	Diet supplementation, primarily with enzymes that aid in digestion of these foods
	Receiving proper medical supervision with better information about the patient's condition

Analyte List

Transglutaminase Antibody ─ definitive test for Celiac Disease

Turn Around Time

The turn around time for this test is 2-3 weeks, unless unforeseen circumstances arise.

Specimen Requirements

1 mL of serum in a gold-topped SST or royal blue-topped no additive tube is the absolute minimum is the absolute minimum. 2 mL of serum is preferred.

CPT Code

82492

Kit Instructions

For blood instructions please click here.

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