Organic Acids Test (OAT) - Nutritional & Metabolic Profile
The Organic Acids Test (OAT) provides an accurate evaluation of intestinal yeast and bacteria. Abnormally high levels of these microorganisms can cause or worsen behavior disorders, hyperactivity, movement disorders, fatigue and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids. The cause of these high levels could include: oral antibiotic use, high sugar diets, immune deficiencies, and genetic factors.
If abnormalities are detected using the OAT, treatments can include supplements, such as vitamins and antioxidants, or dietary modification. Upon treatment, patients and practitioners have reported significant improvement such as decreased fatigue, regular bowel function, increased energy and alertness, increased concentration, improved verbal skills, less hyperactivity, and decreased abdominal pain. The OAT is strongly recommended as the initial screening test.
The Microbial Organic Acids Test (MOAT) is ideal for follow-up to the OAT and is often recommended by practitioners looking for a specific abnormality, to monitor certain microbial imbalances, or to assess treatment efficacy.
Interpretation of the Organic Acids Test by Dr. William Shaw
"After identifying a low serotonin level on an Organic Acid Test (a hallmark functional medicine test), A severely depressed and suicidal man began taking 100mg of 5htp twice a day (5htp is the direct precursor to serotonin). After 2 days, he said his depression virtually disappeared and he was no longer suicidal. I love when I can identify a biochemical glitch and someone can have such a profound emotional turn around."–Dr. Josh Friedman of Integrative Psychotherapy of Omaha
"The Organic Acids Test has brought new meaning to my specialized practice in women's health. This test has allowed me to investigate more deeply the chronic issues that contribute to female related conditions like PMS, uterine fibroids, endometriosis, chronic UTIs and vulvodynia. I have had a great deal of success in treating complicated PMS cases that didn't respond to typical female hormone balancing therapies. Since utilizing the OAT, it has provided me with a variety of information to determine the underlying cause of female related issues. Some of the markers that I find valuable for women's health issues are the bacterial and yeast metabolites, oxalates, B vitamins, vitamin C, and pyroglutamic acid. I have been so impressed by this test that I can't help but want to spread the word about its uses for various women's health conditions!"–Jennifer, N.D.
10 mL of first morning urine before food or drink is suggested. Patient should avoid apples, grapes (including raisins), pears, cranberries and their juices 24 hours prior to specimen collection.
- Evaluate energy production
- Assess central nervous system function
- Reveal high levels of GI yeast and bacteria
- Detect nutritional and antioxidant deficiencies
- Determine problems in fatty acid metabolism
- Identify excess oxalate
Analyte (Metabolite) List of the Organic Acid Test
- Tartaric, Arabinose
- HPHPA (Clostridia marker)
- 4-Cresol (C. difficile)
- DHPPA (beneficial bacteria)
- Homovanillic Acid (HVA)
- Vanillmandelic Acid (VMA)
- HVA/VMA Ratio
- 5-Hydroxyindoleacetic (5-HIAA)
- Quinolinic / 5-HIAA Ratio
- Methylmalonic (Vitamin B12)
- Pyridoxic (Vitamin B6)
- Pantothenic (Vitamin B5)
- Glutaric (Vitamin B2-Riboflavin)
- Ascorbic (Vitamin C)
- 3-Hydroxy-3-methylglutaric (Vitamin Q10-CoQ10)
- N-Acetylcysteine (Glutathione precursor and chelating agent)
- Methylcitric (Vitamin H-Biotin)