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Organic Acids Test (OAT) - Nutritional & Metabolic ProfileGeneral DescriptionThe Organic Acids Test (OAT) provides an accurate evaluation of intestinal yeast and bacteria. Abnormally high levels of these microorganisms can cause or worsen behavior disorders, hyperactivity, movement disorders, fatigue and immune function. Many people with chronic illnesses and neurological disorders often excrete several abnormal organic acids. The cause of these high levels could include: oral antibiotic use, high sugar diets, immune deficiencies, and genetic factors. If abnormalities are detected using the OAT, treatments can include supplements, such as vitamins and antioxidants, or dietary modification. Upon treatment, patients and practitioners have reported significant improvement such as decreased fatigue, regular bowel function, increased energy and alertness, increased concentration, improved verbal skills, less hyperactivity, and decreased abdominal pain. The OAT is strongly recommended as the initial screening test. The Microbial Organic Acids Test (MOAT) is ideal for follow-up to the OAT and is often recommended by practitioners looking for a specific abnormality, to monitor certain microbial imbalances, or to assess treatment efficacy.
Watch the video guide explaining the test report format:
U.S. Patent # 5,686,311 for specific OAT compounds Click here to view the Recommendations By Disorder Chart (PDF) New MarkersThe new and improved OAT has increased the number of tested compounds to 70 and two new ratios have been added. Descriptions of the new markers are listed below: 3-Hydroxyglutaric Acid – Marker for Genetic Disease 3-Methylglutaconic Acid – Marker for Mitochondrial Disorder 4-Cresol – Marker for Bacteria Including Selected Clostridia Tricarballylic Acid – Marker for Exposure to Certain Fungal Contamination in Foods Quinolinic Acid – Marker for Inflammation and Neurotoxicity Inorganic Phosphate – Marker for Bone Function/Vitamin D Deficiency 4-Hydroxybenzoic Acid – Marker for Exposure to Parabens 4-Hydroxyhippuric Acid – Marker for Exposure to Parabens Malic Acid – Marker for Mitochondrial Dysfunction DHPPA – Marker for Beneficial Bacteria N-acetylcysteine (NAC) – Marker for Glutathione Precursor & Chelating Agent Quinolinic Acid/5-HIAA Ratio – Marker for Neurotoxicity and Inflammation Clinical Usefulness
RecommendationsDepending on test results, treatment could include:
Testimonials
“The Organic Acids Test has brought new meaning to my specialized practice in women’s health. This test has allowed me to investigate more deeply the chronic issues that often contribute to female related conditions like PMS, uterine fibroids, endometriosis, chronic UTIs and vulvodynia to name a few. I have had great a great deal of success in treating complicated PMS cases that didn’t respond to typical female hormone balancing therapies. Since utilizing the OAT it has provided me with a variety of information to determine the underlying cause of the female related issue. Some of the markers that I find valuable for women’s health issues are the bacterial and yeast metabolites, oxalates, B vitamins, vitamin C, and pyroglutamic acid. I have been so impressed with this test I can’t help but want to spread the word about its uses for various women’s health conditions!” – Jennifer N., N.D. “Thanks to the Organic Acids Test done in your lab we already have a diagnosis for our six-year-old son. He has a metabolic disorder and is now on a very low fat diet (only polyunsaturated fats), rich in carbohydrates, taking vitamin B2, and avoiding any fasting. He improved extraordinarily and has shown changes and progress in language, and is characterized as almost normal in this area. Thanks to the Organic Acids Test we have managed to save our son, who had autistic characteristics, which he no longer has. We wish to give this testimonial to parents so their children can benefit from doing metabolic testing." – Susana M., Chile Brochures
Analyte (Metabolite) ListCitramalic, 5-Hydroxymethyl-2-furoic, 3-Oxoglutaric, Furan-2,5-dicarboxylic, Furancarbonylglycine, Tartaric, Arabinose, Carboxycitric, Tricarballylic, 2-Hydroxyphenylacetic, 4-Hydroxyphenylacetic, 4-Hydroxybenzoic, 4-Hydroxyhippuric, Hippuric, 3-Indoleacetic, Succinic, HPHPA (Clostridia marker), 4-Cresol (C. difficile), DHPPA (beneficial bacteria), Glyceric, Glycolic, Oxalic, Lactic, Pyruvic, 2-Hydroxybutyric, Fumaric, Malic, 2-Oxoglutaric, Aconitic, Citric, Homovanillic Acid (HVA), Vanillmandelic Acid (VMA), HVA/VMA Ratio, 5-Hydroxyindoleacetic (5-HIAA), Quinolinic, Kynurenic, Quinolinic / 5-HIAA Ratio, Uracil, Thymine, 3-Hydroxybutyric, Acetoacetic, 4-Hydroxybutyric, Ethylmalonic, Methylsuccinic, Adipic, Suberic, Sebacic, Methylmalonic (Vitamin B12), Pyridoxic (Vitamin B6), Pantothenic (Vitamin B5), Glutaric (Vitamin B2-Riboflavin), Ascorbic (Vitamin C), 3-Hydroxy-3-methylglutaric (Vitamin Q10-CoQ10), N-Acetylcysteine (Glutathione precursor and chelating agent), Methylcitric (Vitamin H-Biotin), Pyroglutamic, Orotic, 2-Hydroxyhippuric, 2-Hydroxyisovaleric, 2-Oxoisovaleric, 3-Methyl-2-oxovaleric, 2-Hydroxyisocaproic, 2-Oxoisocaproic, 2-Oxo-4-methiolbutyric, Mandelic, Phenyllactic, Phenylpyruvic, Homogentisic, 4-Hydroxyphenyllactic, N-Acetylaspartic, Malonic, 3-Methylglutaric, 3-Hydroxyglutaric, 3-Methylglutaconic, Phosphoric, Creatinine Specimen Requirements10 mL of first morning urine before food or drink is suggested. Patient should avoid apples, grapes (including raisins), pears, cranberries and their juices 24 hours prior to specimen collection. CPT Codes82131 82507 82570 83150 83497 83605 83921 (63 units) 83945 84207 84210 84585 84591 Kit InstructionsFor urine instructions please click here. Send this page to a friend |
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