Environmental Pollutants Profile
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Sample Report (coming soon) |
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Order Test (coming soon) |
General Description
Increasing exposure to environmental pollutants has been linked to many chronic diseases such as autism spectrum disorders, autoimmune disorders, Parkinson’s disease, and Alzheimer’s disease. Usually, many different individual tests are necessary to determine each pollutant, but the new OrganoGold technology makes it possible in one single test by measuring their urinary metabolites. The Environmental Pollutants Profile screens for 75 different toxic chemicals by testing specific metabolites. Testing for the following pollutants is vital and they are all included in the OrganoGold Panel.
Phthalates
Perhaps the most widespread group of toxic chemicals found in our environment, phthalates have been implicated in reproductive damage, depressed leukocyte function, and cancer.
Parabens
Parabens are frequentlly used as preservatives in a wide range of cosmetic products. They are also used as additives in processed foods and beverages. Parabens were detected in a majority of tumors removed from breast cancer patients.
Trichloroacetic Acid (TCA)
TCA is found in chlorinated drinking water, swimming pools, and lawn care products. It is also a metabolite of certain medications such as Nortec (chloral hydrate) and chemicals used in dry cleaning. TCA is a possible carcinogen.
Vinyl Chloride
Vinyl chloride is an intermediate in the synthesis of several commercial chemicals including polyvinyl chloride (PVC). Exposure to vinyl chloride may cause central nervous system depression, nausea, headache, dizziness, liver damage, and death.
Benzene
Benzene is an organic solvent that is widespread in the environment. Benzene is a by-product of all types of combustion, including cigarette smoke, and is released by outgassing from synthetic materials. Exposure to benzene may cause symptoms of nausea, lack of coordination, and central nervous system depression.
Pyrethrins
Pyrethrins may affect neurological development, disrupt hormones, induce cancer, and suppress the immune system. Pyrethrins are widely used as insecticides. Exposure during pregnancy doubles the likelihood of autism.
Xylenes
Xylenes (dimethylbenzenes) are found in common products such as paints, cleaning fluids, fuel, exhaust fumes, perfumes, and insect repellents. Exposure to xylenes may cause serious adverse health effects including nausea, vomiting, eye, skin, respiratory, and stomach irritation.
Styrene
Styrene is used in the manufacturing of plastics. However, it is found everywhere from car exhaust fumes to building materials. The ability of styrene monomer to migrate from polystyrene packaging to food has been reported.
Organophosphates
Organophosphates are extremely toxic. They are commonly used in insecticide formulations. These compounds are inhibitors of cholinesterase, leading to overstimulation of nerve cells, and causing abnormal behavior including aggression. Exposed children have more than twice the risk of developing Pervasive Developmental Disorder (PDD).
MTBE, ETBE
MTBE and ETBE are gasoline additives used to improve octane ratings. MTBE has been demonstrated to cause adverse health effects in animals. Exposure to these compounds may be due to groundwater contamination.
Solvents
Volatile organic compounds like MTBE, ETBE, benzene, xylene, and styrene, are widely used commercially in the form of household products. These chemicals are carcinogenic and may cause neurological damage.
Click here to view the Recommendations By Disorder Chart (PDF)
Clinical Usefulness
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Identify exposure to multiple environmental toxins |
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Screens for 75 toxic chemicals by testing specific metabolites |
Recommendations
Depending on test results, follow-up can include:
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Reduction of exposure to toxic chemicals |
Brochures
Analyte (Metabolite) List
4-Hydroxybenzoic, 4-Hydroxyhippuric, Quinolinic, Mandelic, 2-Hydroxyisobutyric, Propionylglycine, 2-Methylhippuric, 3-Methylhippuric, Trans, trans-muconic, Phenylglyoxylic, Monoethyl Phthalate (MEP), Phthalic Acid, Dimethylphosphate (DMP), Diethoxyphosphate (DEP), 3-Phenoxybenzoic, Trichloloacetic, Thiodiglycolic
Turn Around Time
The turn around time for this test is 1-3 weeks, unless unforeseen circumstances arise.
Specimen Requirements
5 mL of urine is the absolute minimum. 25 mL of urine is preferred. First morning urine before food or drink is preferred. Patient must avoid apples, grapes (including raisins), pears, cranberries and their juices 24 hours prior to the specimen collection.
CPT Codes
82441 82570 83921*15
Kit Instructions
For urine instructions please click here.
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