Autism Spectrum Disorders
Traditionally, medical and educational establishments have considered autism to be solely a behaviorally-based disorder. The diagnosis of autism has been founded on the observation of behavior and treatment focused primarily on alleviating challenging behaviors. A growing number of individuals within the autism community acknowledge that there is a very real biomedical component to the disorder in which underlying medical issues are often causing or contributing to autistic behaviors. Therefore, to achieve optimal results, it is critical that potential biomedical issues be assessed and included as part of the overall treatment programs for individuals with autistic spectrum disorders.
At The Great Plains Laboratory (GPL), we specialize in providing comprehensive testing that can identify many common biomedical factors that affect the autism community. We are a leader in the research and development of clinically significant tests for the autism community. Several compounds in our Organic Acids Test are patented and only available through GPL. The director of our laboratory, Dr. William Shaw, is also the author of two books dedicated to the biomedical treatment of Autism and PDD. These books are a comprehensive and thorough evaluation of the scientific research and biochemical treatment of autistic spectrum disorders. If you are interested in learning more about biomedical research, we recommend reading Dr. Shaw’s book, Biological Treatments for Autism and PDD for more information.
Numerous clinical studies have shown that individuals with autism spectrum disorder are predisposed to decreased immunity. There are several physiological factors that can contribute to and even cause symptoms of autism.
Some of the most common problems include overgrowth of Candida and Clostridia, inability to detoxify environmental toxins, and development of food intolerances and/or allergies. Each of these problems cause additional complications that make it more difficult for the body to overcome the obstacle at hand. These physical and environmental factors limit the available nutrients to the brain and body which causes damage to cellular, metabolic, and central nervous system functioning. In most cases, when these problems and complications are corrected, the patient’s symptoms are greatly improved.
The immune system is influenced by hundreds of different factors. Every individual with autism exhibits a unique array of behavioral and cognitive symptoms in varying degrees of severity. However, many also experience medical symptoms such as eczema, diarrhea, constipation, rashes, dark eye circles, and visible stomach pain. Biomedical testing may reveal specific abnormalities that could impact some or all of these symptoms when the recommended treatments are carefully followed.
Comprehensive laboratory testing can identify the physiological imbalances that contribute to autism and point to an individual treatment approach. Laboratory testing and environmental assessments can pinpoint causal factors and focus treatment problems. The comprehensive autism panels consist of tests that have been useful for patients with autism.
Information & Resources
- Dr. Shaw's Book: Biological Treatments for Autism and PDD
- Conference Presentation on Organic Acid Testing
- Interview with Dr. Shaw
- A Story on Autism Recovery
- "The Yeast Problem & Bacteria By Products" By Dr. William Shaw
- "Oxalates Control is a Major New Factor in Autism Therapy" By Dr. William Shaw
- "Increased Urinary Excretion of Analogs of Krebs Cycle Metabolites and Arabinose in Two Brothers with Autistic Features" By Dr. William Shaw
- "Assessment of Antifungal Drug Therapy in Autism by Measurement of Suspected Microbial Metabolites in Urine with Gas Chromatography - Mass Spectrometry" By Dr. William Shaw
- "Porphyrin Testing and Heavy Metal Toxicity: Unresolved Questions and Concerns" By Dr. William Shaw
- "Deficient Cholesterol: A Common New Factor in Autism" By Dr. William Shaw
- "Lithium Deficiency: Common in Mental Illness and Social Ills" By Dr. William Shaw
- Click here to view the Recommendations By Disorder Chart (PDF)
Recommended Testing for Autism Patients
- Comi A, Zimmerman A.”Familial Clustering of Autoimmune Disorders and Evaluation of Medical Risk Factors in Autism” Journal of Child Neurology (1999) 14, 388-394
- Stubbs E, Crawford M, Burger D, Vanderark A. “Depressed Lymphocyte Responsiveness in Autistic Children” Journal of Autism and Developmental Disorders (1997) 7, 1573-3432
- Korvatska E, Van de Water J, Anders T, Gershwin M. “Genetic and Immunologic Considerations in Autism” Neurobiology of Disease (2002) 10, 69
- Warren R, Margaretten N, Pace N Foster A. “Immune Abnormalities in patients with Autism” Journal of Autism and Developmental Disorders (2005) 15, 189-197
- Warren R, Foster A, Margartten N. “Reduced Natural Killer Cell Activity in Autism” Journal of the American Academy of Child and Adolesent Psychiatry (1987) 26, 333-335
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